Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...

Proteins are the building blocks of life. These biomolecules comprise chains of amino acids that fold into precise shapes to perform specific jobs in nature. But these elegant structures form only ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction. The ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...