Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

Muscles make up nearly 40% of the human body and power every move we make, from a child's first steps to recovery after ...

Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases In biology’s standard tale of two acids — deoxyribonucleic (DNA) ...

Identifying a few key genes within the vastness of the human genome was once akin to finding the proverbial needle in a haystack. But with the introduction of functional genomic screening, scientists ...

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Künzel, Associate Director in the Functional Genomics department at AstraZeneca, about the application of arrayed ...

CRISPR has a problem: an embarrassment of riches. Ever since the gene editing system rocketed to fame, scientists have been looking for variants with better precision and accuracy. One search method ...

More than 10 million people develop tuberculosis (TB) each year, yet about 40% go undiagnosed. The main culprit is reliance on sputum-based testing, which many patients—particularly those who are ...

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent condition is also linked to other metabolic disorders, including type 2 ...

Fibroblast-activating protein (FAP) expression and first clinical utility of 68Ga-FAPI-PET-CT in testicular cancer patients. Real world data: Survival outcomes of patients with poor prognosis ...

Melissa B. Davis uses CRISPR screening to better understand how cancer affects underrepresented populations and find new potential therapeutic targets.