Continuous processing, already conventional in many manufacturing fields, has been establishing itself in biopharma, which is starting to realize continuous processing’s compelling advantages: ...

Researchers based in Germany have developed a perfusion process for the manufacture of oncolytic viruses. The team from the Max Planck Institute says that the new approach aims to improve virus titers ...

The demand for producing therapeutic recombinant proteins is generating a renewed interest in perfusion cell culture technologies, leading to the development of cell culture media that can support ...

Continuous manufacturing and a quality-by-design development approach are a natural fit. FDA, as well as other regulatory agencies around the world, have for many years been encouraging drug makers to ...

The biopharmaceutical industry has seen substantial growth in recent years, generating novel biotherapeutics and biosimilars at an unprecedented rate. One of the biggest challenges in the industry is ...

ISA106 started with the goal of developing standards, recommended practices, and technical reports on the design and implementation of procedures for automating continuous process operations. The ...

This article overviews some of the benefits and methods of state-based control as it applies to the models defined by the ISA106, Procedure Automation for Continuous Process Operations standards ...