DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

Scientists developed a light-responsive artificial nucleic acid that enables reversible, controllable crosslinking within DNA, opening doors for nanomedicine, DNA nanotechnologies and drug delivery.

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

DNA phosphorothioate modification is a distinctive epigenetic alteration in which a non‐bridging oxygen atom within the DNA sugar-phosphate backbone is replaced by ...

DNA is often seen as the blueprint of life—carrying the code to govern the development and traits of an organism—but “there are things beyond the DNA sequence,” says Xiaoqi Feng, a plant geneticist at ...

Epigenetic modifications such as DNA methylation play a key role in regulating gene expression. Emerging evidence suggests ...

Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...

In a January Science magazine story about his work, the word "heretic" is splashed in teal letters across the page. On those pages and elsewhere, he's been called a "maverick" and a "pioneer," winning ...

A new study has created a map of DNA modification in two regions of the brain critical to learning, memory and emotional regulation. The map offers a benchmark for ensuring stem cell-based models ...