A protein thought to play a supporting role in DNA replication actually facilitates the whole process

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
BioWorld

SY-589 suppresses HR-deficient tumors via POLθ inhibition

DNA polymerase θ (POLθ) is a specialized, error-prone DNA polymerase that promotes the repair of DNA double-strand breaks through theta-mediated end joining (TMEJ), an alternative pathway that ...

USPTO Grants Acurx Pharmaceuticals New Patent for DNA Polymerase IIIC Inhibitors

Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) ("Acurx" or the "Company"), a late-stage biopharmaceutical company developing a new class of small molecule antibiotics for difficult‑to‑treat bacterial ...
Howard Hughes Medical Institute

A Portrait of RNA Polymerase

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...
Pharmabiz

Acurx Pharmaceuticals’ DNA Polymerase IIIC inhibitors receives US patent

Acurx Pharmaceuticals’ DNA Polymerase IIIC inhibitors receives US patent: Staten Island, New York Wednesday, February 4, 2026, 15:00 Hrs [IST] Acurx Pharmaceuticals, Inc., a lat ...