Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...

Once disregarded as “junk DNA,” scientists now know that this molecular dark matter is crucial for determining gene activity ...

Gene regulation is far more predictable than previously believed, scientists conclude after developing the deep learning ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

A new gene editing technique derived from bacterial “jumping genes” can add, remove, recombine and invert DNA sequences, potentially overcoming some of the limitations of CRISPR. The approach is made ...

By Tarun Sai Lomte Blood-based DNA repair and stress-response signals reveal a brief molecular window preceding Parkinson’s ...

An infection with Epstein-Barr virus is a nonevent for most people. But for a subset, the virus can contribute to chronic ...