Scientists at the University of Helsinki have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Extracellular ...

Matrix metalloproteinases (MMPs) are a family of extracellular, zinc-dependent endopeptidases that have emerged as pivotal regulators of neural plasticity and synaptic function. In the brain, MMPs ...

Amyotrophic lateral sclerosis and frontotemporal dementia are heterogeneous diseases that are difficult to fully model in mice. One of the more common forms is caused by hexanucleotide repeat ...

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...