In his new book, “The Catalyst,” Dr. Thomas Cech describes how mRNA in the COVID vaccines encodes the virus’s spike protein. The following is an excerpt from The Catalyst: RNA and the Quest to Unlock ...

A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising ...

Messenger RNA carries genetic information from DNA in the highly protected nucleus out to the rest of the cell, where structures called ribosomes can build proteins according to the DNA blueprint.

Explore the breakthrough of lab-made lncRNA by University of Toronto Engineering for new drug discovery potential.

RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA ...

A commonly used strategy in the development of messenger RNA (mRNA) medicine is based on the destruction of disease-causing mRNA. Achieving the opposite and stabilizing health-promoting mRNA is still ...

How can cells be programmed to respond to complex signals and make targeted decisions, similar to a logical circuit in a computer? Researchers have developed a new approach: an RNA-based genetic ...

This work was supported by funding from New Zealand Ministry of Business Innovation and Employment, Research Trust of Victoria University of Wellington and The Hugh Green Foundation. The recent award ...

Ask a friend what DNA is and, chances are, they have a general idea. Seventy years after scientists discovered the two-stranded helix, DNA (deoxyribonucleic acid) is widely understood as the keeper of ...

Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases In biology’s standard tale of two acids — deoxyribonucleic (DNA) ...