January 18, 2010 — Individuals with treatment-resistant depression tend to have the G/G genotype associated with higher levels of 5-HT 1A autoreceptors, and turning off some of those autoreceptors ...

A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor ...

Nearly 16 million American adults have been diagnosed with attention deficit hyperactivity disorder (ADHD), but evidence suggests that more than 30% of them don't respond well to stimulant medications ...

Gemcitabine Plus Carboplatin Compared With Carboplatin in Patients With Platinum-Sensitive Recurrent Ovarian Cancer: An Intergroup Trial of the AGO-OVAR, the NCIC CTG, and the EORTC GCG Cancer tissue ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

"G-protein coupled receptors, normally, can be activated by specific small molecules that bind in a pocket in the receptor," explained Nicholas Kalogriopoulos, a postdoctoral fellow in the Ting lab ...

More than 1,000 bitter-tasting compounds are recognized by a repertoire of 26 membrane proteins called the type-2 taste receptors (TAS2Rs), also known as the bitter taste receptors 1, 2. Our ...

A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists is to control that process, making cells respond how they want to what ...