Morningstar

Trevi Therapeutics Announces Positive Outcome from Sample Size Re-estimation Resulting in No Change to the Current Sample Size for the Phase 2b CORAL Trial in Idiopathic ...

The trial has reached 75% of the targeted enrollment, and topline results continue to be expected in the first half of 2025 NEW HAVEN, Conn., Dec. 12, 2024 /PRNewswire/ -- Trevi Therapeutics, Inc.
Nature

Effective Sample Size: Quick Estimation of the Effect of Related Samples in Genetic Case-Control Association Analyses

Correlated samples have been frequently avoided in case-controlgenetic association studies in part because the methods for handling them are either noteasily implemented or not widely known.
JSTOR Daily

Large Sample Theory of Estimation in Biased Sampling Regression Models. I

The Annals of Statistics, Vol. 19, No. 2 (Jun., 1991), pp. 797-816 (20 pages) Biased sampling regression models were introduced by Jewell, generalizing the truncated regression model studied by ...
ascopubs.org

A one-sample progression-free survival (PFS) hazard ratio estimate for planning a randomized phase II study (RP2) in mRCC utilizing evidence from RECORD-1.

An evaluation of the societal costs and benefits of adjuvant trastuzumab in the treatment of early HER2neu-positive breast cancer in Singapore. Background: The era of cytostatic cancer agents requires ...
Seeking Alpha

Trevi Therapeutics Announces Positive Outcome from Sample Size Re-estimation Resulting in No Change to the Current Sample Size for the Phase 2b CORAL Trial in Idiopathic ...

Independent Data Monitoring Statistician reaffirmed current sample size to remain at N=160 The trial has reached 75% of the targeted enrollment, and topline results continue to be expected in the ...