From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as their use continues to grow, so does a fundamental challenge: producing RNA ...

Scientists used the auxin-inducible degron 2 system on CTCF, bringing the novel approach to bear on a fundamental protein. CTCF is a critical protein known to play various roles in key biological ...

Scientists have found a new process that happens when an active gene is transcribed from DNA into messenger RNA.. | Cell And ...

Transcription factors are an essential part of gene expression. Some of these proteins are known as master regulators, and they can have an impact on many different biochemical pathways and processes ...

St. Jude Children’s Research Hospital scientists have revealed a previously unknown role for CTCF, a pivotal transcription regulator linked to cancer. CTCF is known by biologists for being a master ...

DNA can be thought of as a vast library that stores all genetic information. Cells do not use this information all at once.

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC. Scientists at St. Jude Children's Research Hospital have found direct ...

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with ...

(Memphis, Tenn.—January 25, 2023) CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children’s Research Hospital used a ...