Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Most of the cells in our body carry the genome, and those cells are constantly bombarded with environmental influences including UV rays, pollution, alcohol, and other exposures that can damage the ...

Cardiff University researchers discovered how a particularly severe type of DNA damage occurs, giving fresh insight into mutation mechanisms that contribute to cancer and inherited genetic diseases.

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A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. The ...

Scientists have revealed exactly how tobacco smoke damages DNA to drive the development of different types of head and neck cancer, a finding that could unlock new treatments and prevention strategies ...

Macquarie University researchers have discovered a naturally occurring protein found in human cells plays a powerful role in repairing damaged DNA—the molecule that carries the genetic instructions ...