BACKGROUND: It remains unclear whether social determinants contribute to major ECG abnormalities (MEA), an early marker of cardiovascular disease, which predicts adverse cardiovascular events and ...

BACKGROUND: Hypertensive disorders of pregnancy (HDP) are associated with increased long-term risk of both maternal and offspring cardiovascular disease. The incidence of HDP has increased ...

Risk prediction has been used in the primary prevention of cardiovascular disease for >3 decades. Contemporary cardiovascular risk assessment relies on multivariable models, which integrate ...

BACKGROUND: Mental stress-induced myocardial ischemia is often clinically silent and associated with increased cardiovascular risk, particularly in women. Conventional ECG-based detection is limited, ...

There is an emerging convergence between atherosclerotic cardiovascular disease and cancer, driven by shared risk factors and overlapping pathophysiologic mechanisms. Traditional factors, such as ...

BACKGROUND: BCR-ABL tyrosine kinase inhibitors (TKIs) have been increasingly linked to pulmonary arterial hypertension (PAH) since 2009, although supporting evidence is limited. Our objective was to ...

Clonal hematopoiesis (CH), the benign clonal expansion of hematopoietic stem cells, is often caused by somatic sequence variations in genes associated with hematologic malignancies. Over the past ...

BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...

Premenopausal women presenting with acute coronary syndrome (ACS) are a unique and often underrecognized patient population. Although they are traditionally considered at lower cardiovascular risk ...

Intro: Myocarditis is an inflammatory cardiac condition that may progress to dilated (DCM) or arrhythmic (ACM) cardiomyopathy. Prior cohort studies indicate genetic factors significantly influence ...

In the largest study to date, we retrospectively included 213 patients evaluated from May 2020 to October 2022 in our CS Clinic diagnosed with presumed CS (169 with isolated CS; 44 with systemic ...

We conducted a prospective open-label study during the 30-day run-in period of the LoDoCo2 trial (Low-Dose Colchicine 2; URL: https://www.anzctr.org.au/; identifier ...