Technology Networks

Proteomics Data Analysis and Bioinformatics: Tools, Pipelines, and Best Practices

Discover how proteomics data analysis and bioinformatics tools enhance mass spectrometry workflows for robust findings.

New Molecular Maps of Bone Could Transform Early Osteoarthritis Detection

Researchers used advanced imaging to uncover early molecular changes in bone that may enable earlier diagnosis of ...

Q&A: Algorithm achieves near end-to-end genome assembly without ultra-long DNA sequencing

Haoyu Cheng, Ph.D., assistant professor of biomedical informatics and data science at Yale School of Medicine, has developed a new algorithm capable of building complete human genomes using standard ...
eLife

SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo

Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...