Background Patients with heart failure (HF) and severe mitral regurgitation (MR) have poor outcomes. Early identification ...

Background Current diagnosis of antiphospholipid syndrome (APS) relies on antiphospholipid antibodies (aPL) testing, but false-positive aPL results and asymptomatic aPL carriers pose significant ...

Background Primary healthcare (PHC) is critical towards achieving Universal Health Coverage (UHC). In Ghana, PHC is organised at the district level and plays a key role in the country’s pursuit of UHC ...

Introduction Community support for individuals with mental health problems is a global public health issue. Poor mental health literacy and high levels of stigmatising attitudes among the general ...

Background Motor and cognitive dysfunctions are common and disabling features in multiple sclerosis (MS) that remain challenging to treat. Here, we aimed to explore the effect of exergames as a ...

9 University of Nottingham School of Health Sciences, Nottingham, UK Objectives To evaluate the feasibility of conducting a full-scale randomised controlled trial to assess the clinical and ...

Risk prediction has been used in the primary prevention of cardiovascular disease for >3 decades. Contemporary cardiovascular risk assessment relies on multivariable models, which integrate ...

Real-world optimization problems often require an external “modeling engine” that computes fitnesses or data that are then input to an objective function. These programs often have much longer ...

Bayes' theorem is a statistical formula used to calculate conditional probability. Learn how it works, how to calculate it ...

BACKGROUND: Mental stress-induced myocardial ischemia is often clinically silent and associated with increased cardiovascular risk, particularly in women. Conventional ECG-based detection is limited, ...