A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists closer than ever to demonstrating how life could have emerged from chemistry ...

Nucleotide synthesis—the production of the basic components of DNA and RNA—is essential for cell growth and division. In most animal cells, this process depends closely on properly functioning ...

Researchers have uncovered the enzyme behind chromothripsis, a chaotic chromosome-shattering event seen in about one in four ...

After a long search, RIKEN researchers have identified an enzyme crucial for keeping lipid-linked sugar chains in check in yeast cells. This finding, published in the Journal of Cell Biology, reveals ...

Mitochondria possess their own mRNA translation system, mediated by specialized mitoribosomes. Dysregulation of mitochondrial translation disrupts metabolic homeostasis and is linked to various ...

Despite the availability of effective antihypertensive therapies, global blood pressure control rates remain unacceptably low. Contributing factors, such as low treatment adherence, therapeutic ...

A long-standing mystery in bile acid biology has been solved. Bile acids are often introduced as digestion helpers, but they are also powerful chemical messengers that help coordinate metabolism ...