Q&A: Algorithm achieves near end-to-end genome assembly without ultra-long DNA sequencing

Haoyu Cheng, Ph.D., assistant professor of biomedical informatics and data science at Yale School of Medicine, has developed ...
GitHub

Ancestral sequence reconstruction using generative models

Ancestral sequence reconstruction (ASR) is a foundational task in evolutionary biology, providing insights into the molecular past and guiding studies of protein function and adaptation. Conventional ...
IEEE

Regression Models for Estimating Similarity Score of the Optimal Expected Multiple Sequence Alignments

Abstract: Sequence alignment is a crucial tool in biological research. Alignment quality is typically assessed using scores, but these do not guarantee optimality. Estimating the optimal alignment ...
IEEE

Riemannian Time Warping: Multiple Sequence Alignment in Curved Spaces

Abstract: Temporal alignment of multiple signals through time warping is crucial in many fields, such as classification within speech recognition or robot motion learning. Almost all related works are ...
Frontiers

Sequence-based prioritization of i-Motif candidates in the human genome

1 Department of Science and High Technology, University of Insubria, Como, Italy 2 Center of Neuroscience Research, University of Insubria, Busto Arsizio, Italy Introduction: i-Motifs (iMs) are ...
ScienceCodons

EMBL File Format Converter

The EMBL File Format Converter is a specialized tool that converts biological sequence data from the EMBL format to various standard formats. It streamlines bioinformatics workflows by accurately ...
C&EN

Structure Prediction of Alternate Frame Folding Systems with AlphaFold3

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. AlphaFold has ...
ScienceCodons

STOCKHOLM File Format Converter

Our STOCKHOLM File Format Converter is a specialized bioinformatics utility designed to improve interoperability among multiple sequence alignments (MSAs). This tool expertly converts alignments from ...
Scientific Research Publishing

Criscuolo, A. and Gribaldo, S. (2010) BMGE (Block Mapping and Gathering with Entropy): A New Software for Selection of Phylogenetic Informative Regions from Multiple Sequence ...

ABSTRACT: Genomic surveillance has proven to be a critical source of information for understanding and responding to the COVID-19 pandemic. In Africa, genomic surveillance was very limited, and few ...