Recently, bioinformatics has emerged as a prominent subject within computer science, providing substantial insights into biology and human-related information. The primary challenge in bioinformatics ...

Abstract: Modern sequence alignment tools rely on seed-based anchoring to efficiently align large-scale sequencing data. Minimizers are widely used for seed extraction but often generate excessive and ...

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MSA Transformer takes a multiple sequence alignment as an input to reveal conservation patterns, and is trained with Masked Language Modeling objectives to capture epistasis [1]. Previous research ...

Ancestral sequence reconstruction (ASR) is a foundational task in evolutionary biology, providing insights into the molecular past and guiding studies of protein function and adaptation. Conventional ...