Endocrinology Advisor

Prepregnancy HOMA-IR Independently Associated With Future GDM Risk

Higher prepregnancy HOMA-IR is independently associated with an increased risk for gestational diabetes mellitus years before conception.
Healio

Agent Orange exposure may increase acral melanoma risk for veterans

Prior exposure to Vietnam War-era herbicide, Agent Orange, may increase veterans’ odds of having acral melanoma by ...
Gut

Rise of prediagnostic molecular profiling in inflammatory bowel disease—can we close the door before the horse has bolted?

Inflammatory bowel disease (IBD) is typically diagnosed after the onset of symptoms in the context of established, ...
AHA/ASA Journals

Criteria to Assess the Predictive and Clinical Utility of Novel Models, Biomarkers, and Tools for Risk of Cardiovascular Disease: A Scientific Statement From the American Heart ...

Risk prediction has been used in the primary prevention of cardiovascular disease for >3 decades. Contemporary cardiovascular risk assessment relies on multivariable models, which integrate ...
The Lancet

Statin safety: when warnings outlive the evidence

More than 30 years after the Scandinavian Simvastatin Survival Study showed that statins save lives, their full public health potential remains unrealised. Statins are underused worldwide, and as a ...
AHA/ASA Journals

Second- and Third-Generation BCR-ABL Tyrosine Kinase Inhibitors and the Risk of Pulmonary Arterial Hypertension: A Prevalent New-User Design

BACKGROUND: BCR-ABL tyrosine kinase inhibitors (TKIs) have been increasingly linked to pulmonary arterial hypertension (PAH) since 2009, although supporting evidence is limited. Our objective was to ...