This proteomics-driven approach to drug discovery improves target validation and uncovers insights into undruggable proteins, ...

Proteomics as a concept concerns the study of the complete set of proteins expressed by an organism since the molecules carry out nearly every bodily activity.

Researchers used advanced imaging to uncover early molecular changes in bone that may enable earlier diagnosis of ...

Explore AI in drug discovery and its journey from promise to proof in 2025 with significant achievements and challenges faced.

Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease ...

Comprehensive residue-level mapping of amyloid-beta recognition reveals how sequence variants, post-translational modifications, and aggregation state shape antibody specificity, thereby guiding ...

Scientists have identified a crucial mechanism that allows plants to shape their vascular systems, determining whether they ...

By Hugo Francisco de Souza Emerging research suggests reversible RNA editing mechanisms may influence heart disease biology while opening new avenues for biomarkers and next-generation cardiovascular ...

Inflammatory bowel disease (IBD) is typically diagnosed after the onset of symptoms in the context of established, ...

Risk prediction has been used in the primary prevention of cardiovascular disease for >3 decades. Contemporary cardiovascular risk assessment relies on multivariable models, which integrate ...