Scientists have identified a crucial mechanism that allows plants to shape their vascular systems, determining whether they grow soft edible storage organs or develop the rigid woody tissue ...

Proteomics as a concept concerns the study of the complete set of proteins expressed by an organism since the molecules carry ...

Comprehensive residue-level mapping of amyloid-beta recognition reveals how sequence variants, post-translational modifications, and aggregation state shape antibody specificity, thereby guiding ...

This overview explains how proteomics sample preparation underpins mass spectrometry performance. It details best practices ...

Researchers have proposed a novel integrated framework to understand the complex progression of autoimmune skin diseases. A ...

The partnership is supported by the Michael J. Fox Foundation, which seeks to better understand aSyn protein's role in Parkinson's disease.

This study presents an advance in efforts to use histone post-translational modification (PTM) data to model gene expression and predict epigenetic editing activity. Such models are broadly useful to ...

Macrophage polarization is central to immune homeostasis and disease pathogenesis. It is achieved through complex regulatory networks mediated by post-translational modifications (PTMs). This review ...

ABSTRACT: Epigenetic mechanisms regulate and stabilize a broad range of biological processes without altering the primary DNA sequence. This regulation is achieved through DNA methylation, ...

A new study published in the journal Cell Death & Disease by researchers at the University of Alabama at Birmingham has identified a potential therapeutic target for ...