This article and associated images are based on a poster originally authored by Marina Fedorova and Ian Hiles and presented at ELRIG Drug Discovery 2024 in affiliation with GSK. This poster is being ...

Making proteins for research or therapies often starts with cell-line development. In many applications, genetic engineering is used to optimize a cell line for producing high levels of the intended ...

Scientists at the Yong Loo Lin School of Medicine, (NUS Medicine), have identified a molecular switch that helps aging brains maintain their ability to generate new nerve cells. The discovery centers ...

Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.

MIT researchers have built an AI language model that learns the internal coding patterns of a yeast species widely used to manufacture protein-based drugs, then rewrites gene sequences to push protein ...

Gas vesicles are among the largest known protein nanostructures produced and assembled inside microbial cells. These hollow, ...

This article is based on a poster originally authored by Sunidhi Shetty, Narasimha Murthy Bandaru, Anna Moberg and Marco Manni, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

The testing of archival biopsy specimens has found “near-universal expression” of DLL3 in SCLC tumors, leading researchers to ...

Digital Pathology–Based Multimodal Artificial Intelligence Scores and Outcomes in a Randomized Phase III Trial in Men With Nonmetastatic Castration-Resistant Prostate Cancer FGFR2b protein ...