A randomised controlled trial evaluates whether a structured self management intervention improves skills and quality of life ...

Following the frequent suspicions regarding the safety of cholesterol-lowering drugs in the pre-statin era,1 statins have been a recurrent object of various concerns and alarming news. For example, ...

Kathryn Snow does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

Background In randomised controlled trials (RCTs) of interventions that aim to prevent sports injuries, the intention-to-treat principle is a recommended analysis method and one emphasised in the ...

Objective To assess effectiveness equivalence between two commonly prescribed 12-week exercise programmes targeting either the quadriceps or the hip muscles in patients with patellofemoral pain (PFP).

Fiona Fidler receives funding from the Australian Research Council and IARPA. Randomised controlled trials are the gold standard in medical research. Researchers divide participants into two groups ...

A cluster randomised trial (CRT) is a randomised controlled trial in which pre-existing groups, called clusters, of individuals are randomly allocated to treatment arms. For example, clusters may be ...

The video below shows how a randomised trial works. It is about 2 minutes long. Randomised trials have at least 2 different treatment groups. The people taking part are put into one of the groups at ...