High-dimensional -omics data such as genomic, transcriptomic, and metabolomic data offer great promise in advancing precision medicine. In particular, such data have enabled the investigation of ...

Statistical methods now being used in adaptive biomarker-driven clinical trials are reviewed. Some previous paradigms for clinical trial design can limit the development of more effective methods on ...

Abstract: Assumptions play a pivotal role in the selection and efficacy of statistical models, as unmet assumptions can lead to flawed conclusions and impact decision-making. In both traditional ...