Metal alloys crack and fail through a mechanism called "fatigue" when repeatedly loaded and strained. While it is well known how to design alloys to withstand static loads and pressures, it is very ...

Abstract: In the last decades, dynamic resource programming in partial resource domains has been extensively investigated for single-time-slot optimizations. However, with the emerging real-time media ...

The authors provide a direct, single-molecule quantification of the force-dependent structural dynamics of the giant nesprin-2 protein under physiologically relevant forces and loading rates. They ...