The Nobel Prize in physiology or medicine was awarded Monday to Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, tiny pieces of genetic material that alter how genes work at ...

A flow cytometry-based approach to isolate extracellular vesicles is evaluated and its impact on microRNA cargo is revealed, showing reduced molecular diversity while preserving core functional ...

Mir195 enables Ebf1-deficient hematopoietic progenitor cells to mature into B cells, suggesting some miRNA can substitute for transcription factors in differentiation.

The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA and its pivotal role in post-transcriptional gene regulation.

Background: MicroRNA-1 (miR1) plays a critical role in maintaining cardiac homeostasis. Full knockout of miR1 results in postnatal lethality. While prior studies have primarily focused on the ...

Human Sperm Bank of The First Hospital of Lanzhou University, Lanzhou, Gansu 730013, China The First Clinical Medical College of Lanzhou University, Lanzhou, Gansu 730000, China In an article by Sun ...

Announcing a new article publication for BIO Integration journal. Liver fibrosis is caused by excessive extracellular matrix accumulation, which in turn is driven by activation of hepatic stellate ...

MicroRNAs are essential for Purkinje cells to develop their characteristically elaborate dendritic arbors. When Scripps Research scientists temporarily turned off microRNA function during development, ...

Summary: A new study reveals that microRNAs—tiny regulators of gene expression—play a crucial role in shaping Purkinje cells, rare brain neurons linked to movement and neurodevelopmental disorders.

MicroRNAs (miRNAs) are small, non-coding RNA molecules, typically 21–23 nucleotides in length, that play a crucial role in regulating gene expression. They function by binding to complementary ...

Victor Ambros receives funding from the U.S. National Institutes of Health. The Conversation Weekly podcast caught up with Victor Ambros from his lab at the UMass Chan Medical School to learn more ...