PharmExec

The Next Generation of Trial Designs: Supplementing Trials with Real-World Data

Real-world data (RWD) is transforming clinical research, augmenting existing randomized controlled trial (RCT) data to de-risk studies and improve generalizability. With regulators setting clearer ...

How To Speed Up the Search for Cures Through a Change in Probability Theory

If the FDA follows through with the proposed guidelines, and they are not fatally twisted by pressure from the medical ...
IEEE

Homotopic Gaussian Mixture Filtering for Applied Bayesian Inference

Abstract: Bayes' rule, although a powerful framework for performing state estimation, is often intractable for real-world, nonlinear dynamic systems. As a result, estimation algorithms typically rely ...
BMJ

FDA is now “open to bayesian statistics”: transformational change or new Pandora’s box?

The US Food and Drug Administration (FDA) is now “open to bayesian statistics,” contrasting this with the frequentist approach that the agency and the drug industry have historically relied on for ...
IEEE

Matrix-Inversion-Free Sparse Bayesian Learning for High-Resolution Radar Imagery via Improved Variational Inference

Abstract: Sparse Bayesian learning (SBL) is an advanced statistical framework that dominantly enhances the sparse features of targets of interest in radar imagery. A widely adopted strategy for ...