For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments that can control gene activity in specific cells. These sequences, called ...

The power of artificial intelligence (AI) and advanced computing has made it possible to design genetic sequences encoding for diverse biological applications, such as proteins that form the building ...

Genetic features known as transposons make up a large portion of many mammalian genomes, including humans', and they are now known to play a variety of roles. Some transposable elements (TEs) could be ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...