This study addresses endosomal escape in oligonucleotide therapies and how engineered peptides can enhance intracellular drug delivery efficiency.

Right now, molecules in the air are moving around you in chaotic and unpredictable ways. To make sense of such systems, physicists use a law known as the Boltzmann distribution, which, rather than ...

Risk prediction has been used in the primary prevention of cardiovascular disease for >3 decades. Contemporary cardiovascular risk assessment relies on multivariable models, which integrate ...

Andrew Bloomenthal has 20+ years of editorial experience as a financial journalist and as a financial services marketing writer. Samantha (Sam) Silberstein, CFP®, CSLP®, EA, is an experienced ...

Objective This study investigated perinatal depressive symptoms among pregnant and postpartum Filipino women. Design Cross-sectional survey. Setting The Philippines. Participants Participants were ...

Background A more nuanced understanding of behavioural responses to incentives over time, particularly after they are removed, could guide more effective interventions. In this study, we build on the ...

In this nationwide cohort study, trans Australians experienced substantially elevated mortality risk. Tailored policy responses are needed to address premature mortality in trans populations.

Adam Hayes, Ph.D., CFA, is a financial writer with 15+ years Wall Street experience as a derivatives trader. Besides his extensive derivative trading expertise, Adam is an expert in economics and ...

A machine learning model incorporating functional assessments predicts one-year mortality in older patients with HF and improves risk stratification beyond established scores. Functional status at ...