Researchers have made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work points to potential applications in health, ...

Ensemble map of protein structure. The team’s approach integrates different NMR data to create a map of how different parts of a molecular structure move. Tokyo, Japan – Researchers from Tokyo ...

Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up biochemical reactions (catalysis) in cells—have adapted to the habitats of ...

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects in IVD function lead to toxic accumulation of metabolites such as isovaleric ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance. Key details in the enzyme-driven biosynthesis of a natural molecule with ...