Nucleotide synthesis—the production of the basic components of DNA and RNA—is essential for cell growth and division. In most ...
Analysis from continued follow-up of Phase 1/2 clinical trial data in Hunter syndrome (MPS II) reinforces potential for tividenofusp alfa (DNL310) to address full disease spectrumLaunch readiness ...
JCR Pharmaceuticals Co., Ltd. (TSE 4552; "JCR"), a global specialty biopharmaceutical company dedicated to developing therapies for rare and genetic diseases, today announced the presentation of four ...
A new discovery by researchers from Adelaide University, in collaboration with Denmark’s Carlsberg Research Laboratory, will allow barley growers to optimise seed dormancy for their crops and improve ...
The inhibitor and substrate compete for the same binding site (or the active site) on the enzyme. The inhibitor decreases the enzyme’s capacity to bind the substrate, but this impact may be ...
Department of Microbiology, The Ohio State Biochemistry Program, The Center for RNA Biology, The Ohio State University, Columbus, OH, United States Among tRNA modification enzymes there is a ...
Researchers at the University of Basel have repurposed a natural enzyme so that it catalyzes a highly challenging chemical reaction. Their approach opens new possibilities for synthesizing complex ...
Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The translocation of DNA in polymerase (Pol) enzymes is a critical step for ...