Abstract: A mathematical model for the excitation-contraction mechanism (E-C coupling) in cardiac cells has been formulated, based on the works of Tang and Othmer (1994), Luo and Rudy (1994), Jafri ...

This study presents a valuable finding that the biomechanical force of heart contractility is required for robust endocardial id2b expression, which in return promotes valve development and myocardial ...

The control of muscle contraction is usually described in terms of excitation–contraction coupling or muscle activation. Muscle relaxation has received much less attention, although its control is ...

Institute of Intelligent Sport and Proactive Health, Department of Health and Physical Education, Jianghan University, Wuhan, China Sarcopenia and AD are both classic degenerative diseases, and there ...

Cardiovascular and cerebrovascular diseases, collectively termed cardiovascular diseases, are the leading causes of death globally according to the World Health Organization. Cardiovascular diseases ...

ABSTRACT: Impaired excitation-contraction coupling occurs in eccentric contraction (ECC)-induced damaged muscles. It has been suggested that sarcoplasmic reticulum (SR) is susceptible to damage in the ...

The possibility that the inotropic action of epinephrine might be mediated through an effect on the excitation-contraction coupling process was explored, using techniques for measurement of isometric ...