Researchers in China have reported a novel adeno-associated virus strategy that enables efficient in vivo reassembly and expression of large therapeutic genes, addressing a long-standing ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the ...

The study aims to enrol 12 adults with ALS at locations in Europe, the UK and US.

Nine-year follow-up of gene therapy in haemophilia B confirms long-term safety and reduced bleeding, though full capsid ...

Validated, tissue-specific library enables customisable and controllable liver-targeted gene expression with high specificity and minimal off-target activity in muscle tissue ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...

Yeast-based protein expression systems will likely play an important role in vaccine production during future pandemics.

Multichain biotherapeutics continue to be a promising therapeutic modality. “These therapeutic recombinant proteins are typically assembled from at least three distinct polypeptide chains,” says ...

All aspects of upstream bioprocessing are under pressure to increase expression titers and improve product quality (PQ). To date, major advancements in the glutamine synthetase (GS) system for Chinese ...