As we age, we don’t recover from injury or illness like we did when we were young. But new research from UC San Francisco has found gene regulators that turn genes on and off that could restore the ...

Background Intestinal fibrosis, a hallmark complication of Crohn’s disease (CD), frequently progresses to stricture formation and surgical intervention. Fibroblast metabolic reprogramming is important ...

On Wednesday, FibroBiologics, Inc. (NASDAQ: FBLG) submitted a new patent application with the U.S. Patent and Trademark Office (USPTO). The patent application covers a proprietary fibroblast-derived ...

Heart failure occurs when the heart can no longer pump blood efficiently to meet the body’s needs. Beyond weakened muscle cells, new research highlights the hidden role of fibroblasts—supporting cells ...

The Human Cell Atlas project has delivered a fresh tranche of data mapping fibroblasts in healthy and diseased skin and pointing to drug targets with potential in multiple diseases across a range of ...

Healing from any injury involves a delicate balance between scarring and inflammation — two processes that can wreak havoc as well as make repairs. When the injury is to the brain, the balance is that ...

In patients surviving myocardial infarction, adipose tissue infiltration within the scar is a common pathological finding and has been suggested to contribute to dysfunction and arrhythmogenesis.

NUDT21 regulates fibroblast senescence and is significantly decreased in aged and fibrotic lungs, impacting IPF progression. Alternative polyadenylation (APA) and NUDT21 downregulation enhance STAT3 ...

18 F-labeled fibroblast activation protein inhibitor tracer (18 F-FAPI-42) PET imaging can detect fibroblast activation in the myocardium among patients with dilated cardiomyopathy (DCM), according to ...

Imagine this: you’re in the middle of an important project, juggling deadlines, and collaborating with a team scattered across time zones. Suddenly, your computer crashes, and hours of work vanish in ...