This new article publication from Acta Pharmaceutica Sinica B, discusses how an innovative and stable mRNA-LNP microneedle vaccine elicits humoral and multifunctional cellular immune responses.

The innate humoral system is the first to respond to pathogens through several soluble components in the body fluids. These compounds (C-reactive protein, amyloid A serum, transferrin, α-2 ...

Finland was the first country to offer the zoonotic avian influenza A(H5N8) vaccine manufactured by Seqirus to at-risk occupational groups following the extensive clade 2.3.4.4b A(H5N1) outbreak ...

A simple and widely deployable microneedle (MN) vaccine delivery system (mLNP-man-MN) was developed for mannose-modified LNPs (mLNP-man) loaded with mRNA encoding the SARS-CoV-2 spike receptor-binding ...

Why are some people fiery and impulsive while others are calm and measured? The ancient Greeks believed they had the answer, and their theory shaped medicine, philosophy and psychology for more than ...

Introduction: Short cycles of ischemia/reperfusion (I/R) in a tissue/organ remote from the heart reduce myocardial I/R injury. Such remote ischemic conditioning (RIC) is operative in all species ...

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...

Abstract: A novel approach for power system voltage control implemented on the basis of the learning humoral immune response was proposed previously by the authors (2002). This proposed humoral immune ...

Multicellular organisms have evolved an immune system that fights off infections. Not only does it fight off infections, it also remembers which pathogens have been encountered, and responds more ...

ABSTRACT: In order to find an effective immune preparation to control tilapia streptococcus disease, the Streptococcus agalactiae surface protein serine protease C5a peptidase (ScpB) was cloned and ...

Sensitive and specific biomarkers can help accurately identify complex diseases early as well as provide clinicians with information useful for directing treatment, identifying disease endotypes, ...