Hematopoietic stem cells (HSCs) emerge in vertebrate embryos under the coordinated regulation of multiple signaling pathways. Despite advances in developmental biology, robust protocols for generating ...

Signaling module for vehicle preps covers emergency roadside assistance. New disclosures show Trump bought bonds affected by government policy changes The Standoff That Brought the Big Ten’s $2.4 ...

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...

1 College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou, China 2 Institute of Life and Health, Zhengzhou University of Light Industry, Zhengzhou, China The Notch ...

The evolutionarily conserved Notch signaling pathway is essential for cell-fate determination, organogenesis, and tissue homeostasis. Notch receptors and their ligands are transmembrane proteins with ...

A key part of resignalling the busiest routes in south east London is taking place over the August bank holiday. As part of a £90 million project, the signalling through Lewisham, from New Cross to ...

Rail TempEst ™, a new software application from KB Signaling Inc. (KBS), provides data that goes “beyond forecasts and assumptions toward real-time, high-resolution rail temperature and measurements ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights ...