Researchers used advanced imaging to uncover early molecular changes in bone that may enable earlier diagnosis of ...
The final, formatted version of the article will be published soon. Infectious diseases continue to pose major threats to global public health, owing to the persistent emergence of novel and ...
AZoLifeSciences on MSN
Proteomics approaches to overcome undruggable targets in disease
This proteomics-driven approach to drug discovery improves target validation and uncovers insights into undruggable proteins, ...
Comprehensive residue-level mapping of amyloid-beta recognition reveals how sequence variants, post-translational modifications, and aggregation state shape antibody specificity, thereby guiding ...
This overview explains how proteomics sample preparation underpins mass spectrometry performance. It details best practices ...
Recently, the research team led by Professor Jun Pang from the Department of Urology at The Seventh Affiliated Hospital of Sun Yat-sen University discovered that cyclin-dependent kinase 12 (CDK12) can ...
Researchers have proposed a novel integrated framework to understand the complex progression of autoimmune skin diseases. A ...
Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as "tauopathies"). New research led by Boston Children's Hospital challenges the current ...
Abstract: O-linked glycosylation is a complex form of posttranslational modification in human proteins that plays a crucial regulatory role in a wide range of cell types. It is intimately involved in ...
Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as "tauopathies"). New research led by Boston Children's Hospital challenges the current ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results