Abstract: Cyclic protein oligomers play vital roles in many biological processes and have captured the attention of protein designers. An important step of protein design is to predict the quaternary ...
Cryo-electron microscopy (cryo-EM) is a key technology for determining the structures of proteins, particularly large protein complexes. However, automatically building high-accuracy protein ...
The sequence—structure (ensemble)—function relationship is central to biology. Protein dynamics in the structure ensemble determine function and mutation effects, and are widely used to study ...