Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding where ...
Localizatome contains comprehensive information about the stress-induced protein localization changes within living cells. It provides open access to subcellular protein localization data through a ...
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Spatial proteomics: Mapping protein organization across cells and tissues
Advancements in spatial proteomics enable detailed tissue mapping, linking protein localization to disease mechanisms and enhancing translational research.
Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...
What is Photoactivated Localization Microscopy? Photoactivated Localization Microscopy (PALM) is a super-resolution imaging technique that allows for the visualization of biological structures at the ...
Therapies that are sensitive to multiple biomarkers could allow medicines to reach only the areas of the body where they are needed. The diagram above shows three theoretical biomarkers that are ...
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