During development, many crucial genes help organisms form properly. One of those genes is myogenic determination gene number 1 (MyoD), which can exert a powerful influence as a “genome organizer." It ...
Tomato fruit ripening is a tightly regulated process involving hormonal signaling, metabolic reprogramming, and epigenetic modulation. Ethylene plays a pivotal role in climacteric fruit ripening, but ...
A high throughput screen of >30,000 diverse repressor domains from across the tree of life identifies repressor domains with unique structures that underpin enhanced epigenetic effector domain potency ...
In this important study, the authors explore ER stress signaling mediated by ATF6 using a genome-wide gene depletion screen. They find that the ER chaperone Calreticulin binds and directly represses ...
Most of our genome is often written off as “junk DNA”, meaning it doesn’t encode for genes that get made into proteins. This so-called junk consists of accumulated DNA elements like viral DNA that got ...
National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, Jiangnan University, Wuxi 214122, Jiangsu, P. R. China Jiangsu Provincial Engineering Research Center for ...
African trypanosomes evade host immune clearance by antigenic variation, causing persistent infections in humans and animals. These parasites express a homogeneous surface coat of variant surface ...
The brown planthopper (BPH) is the most destructive pest of rice. The MYB transcription factors are vital for rice immunity, but most are activators. Although MYB22 positively regulates rice ...
Atrial fibrillation (AF) is a highly prevalent condition that can cause or exacerbate heart failure, is an important risk factor for stroke, and is associated with pronounced morbidity and death.
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