No man is an island, even when they’ve turned their isolated lighthouse residence into Home Alone at the end of the world. Though the tough SOB played by Jason Statham in Shelter might be the kind of ...
Abstract: Cyclic peptides become attractive therapeutic candidates due to their diverse biological activities. However, existing deep learning-based sequence design models, such as ProteinMPNN, are ...
Over 8,000 years ago, early farming communities in northern Mesopotamia were already thinking mathematically—long before numbers were written down. By closely studying Halafian pottery, researchers ...
This important work introduces a family of interpretable Gaussian process models that allows us to learn and model sequence-function relationships in biomolecules. These models are applied to three ...
All of modern mathematics is built on the foundation of set theory, the study of how to organize abstract collections of objects. But in general, research mathematicians don’t need to think about it ...
In recent years, the integration of computational and machine learning techniques has dramatically advanced our understanding of protein function and engineering. As proteins underpin virtually every ...
Abstract: Graphons are limit objects of sequences of graphs and are used to analyze the behavior of large graphs. Recently, graphon signal processing has been developed to study signal processing on ...
Decades of research has viewed DNA as a sequence-based instruction manual; yet every cell in the body shares the same genes – so where is the language that writes the memory of cell identities?