Abstract: Single-cell RNA sequencing (scRNA-seq) technology has made significant breakthroughs in genomics research in recent years, enabling in-depth analysis of gene expression profiles at the ...
Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...
This article and associated images are based on a poster originally authored by Marisa Amato and presented at ELRIG Drug Discovery 2025 in affiliation with Singleron Biotechnologies GmbH. This poster ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
For centuries, scientists have recognized that certain illnesses can run in families, an idea that dates back to Hippocrates. Over time, researchers have become increasingly skilled at uncovering how ...
notebooks_2020_10_08_bulk_RNAseq_pathwayAnalysis.ipynb - a bulk RNAseq analysis tutorial I wrote using kallisto quantified data (R) youtube link for a walkthrough of ...
Abstract: Gene panel selection aims to identify the most informative genomic biomarkers in label-free genomic datasets. Traditional approaches, which rely on domain expertise, embedded machine ...
When cells expire, they leave behind an activity log of sorts: RNA expelled into blood plasma that reveals changes in gene expression, cellular signaling, tissue injury and other biological processes.
Variant allele frequencies between RNA-seq and DNA-seq showed strong correlations. Among tumors sequenced with diagnostic intent, 37 received new diagnoses, representing 1.9% of evaluable cases. An ...
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