Likelihood Ratio Statistics for DNA Mixtures Allowing for Drop-Out
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Likelihood Ratio Statistics for DNA Mixtures Allowing for Drop-Out
Likelihood Ratio Statistics for DNA Mixtures Allowing for Drop-Out
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Concept Check: The Constrained Maximum Likelihood EstimatorIn the general form of the likelihood ratio test, we have an unknown parameter θ ∈ Rd and we are deciding between two hypotheses of the form:Ho: (θ0, θ1) = (θ01, θ84)Hi: (θ0, θ1) ≠ (θ01, θ84)for some θ0 ≠ 0.Thus, θ0, the region defined by the null hypothesis, is:θ0 = v ∈ Ra | (vθ1, vθd) = (θ0, θ1, ..., θd)where θ1, θ2, ..., θd consists of known values.The likelihood ratio test involves the test-statistic:Tn =
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LIKELIHOOD RATIOS EXPLAINED AND CALCULATED Now we're going to talk about to most crucial values for special tests: The positive and negative likelihood ratio, abbreviated as LR and LR-. Those two values basically determine to what degree a positive or negative test will influence the probability of your patient actually having (or not having) the disease you were testing for in the first place. The literature describes a LR above 10 is and a LR-
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